Vol. 1 Issue 08    Friday, October 26, 2007
“Visit us at CPhI India 2007, at Bombay Exhibition Centre, Mumbai, India. November 25 - 27  2007, at Hall- 5, Stand No: B12”
  APIs

 Commercial Scale
 Alendronate sodium
 Arteether
 Artemether
 Artesunate
 Azithromycin
 Cetirizine dihydrochloride
 Chloramphenicol palmitate
 Clopidogrel bisulphate
 Coenzyme Q10
 Dihydroartemisinin
 Erythromycin base
 Erythromycin estolate
 Erythromycin ethyl succinate
 Erythromycin oxime (intermediate)
 Erythromycin phosphate
 Erythromycin propionate
 Erythromycin stearate
 Isoniazid
 Lisinopril dihydrate
 Losartan potassium
 Pyrazinamide
 Rifampicin
 Roxithromycin
 Sodium valproate
 Valproic acid
 Venlafaxine hydrochloride
 Zoledronic acid
 Zopiclone

 Pilot Plant Scale
 Carvedilol
 Clarithromycin
 Pioglitazone hydrochloride
 Rosiglitazone maleate
 Valsartan

 R & D Scale

 Lumefantrine
 Pamidronate disodium
 Perindopril erbumine
 Zolpidem tartrate

 Development
 Benazepril hydrochloride
 Candesartan
 Desvenlafaxine
 Glipizide
 Irbesartan
 Levocetirizine
 Rifabutin
 Rifapentine
 Ramipril
 Risedronic acid
 Telmisartan


      Product under patent  offered  only
      for exempted research, clinical and
      development  purposes. Only  non-
      infrining   products   and  processes
      are offered, subject to patent status
      verification by client.
Services

   • Custom Syntheses

   • Contract Manufacturing

   • FTE Research

   • Analytical Support

   • Intermediates & APIs

   • Building Blocks

Happy Diwali                       Happy Diwali                      Happy Diwali
    
    Diwali : The festival of lights


    The growing ethnic  and cultural diversity of  Indian community  throughout       the world  provides the  opportunity  to  participate in the celebrations  and     rituals of Diwali festival that enhances the  feelings of  being part of a close
    -knit group of Indians. Most Diwali celebrations around the  world focus  on     family and friends and it is a time to reflect on the  past and  envision for a     future, perhaps, in a world where people live together in harmony.
The  festival  of  Diwali  heralds  the  victory of good  over evil, light  over  darkness,  knowledge  over ignorance, joy, mirth  and
happiness in the life of every individual.

Press release in ‘The Economic Times’

Calyx Chemicals to set up R&D centre in Mumbai
12 Oct, 2007, 2052 hrs IST, PTI

NEW DELHI: Drug  firm  Calyx Chemicals and  Pharmaceuticals is investing  Rs 40 crore  to set up a research and development centre in Dombivli near Mumbai as part of its plans to expand its research and manufacturing services business.

"Going forward, we want to expand our  Contract Research and  Manufacturing  Services (CRAMS)  capability and  would  invest
Rs 40 crore in setting up a R&D centre  near Mumbai," Calyx  Chemicals  and  Pharmaceuticals President (R&D) and Executive Director Bansi Lal told media on the sidelines of a CII event.

He said the R&D centre would employ up to 300 scientists  and is expected to  be  operational by early next year. The company
is half way through construction and installation of equipment at the centre, he added.

"With the  R&D centre operational by early 2008 and  expansion in our capacities, we would like to be a major player in CRAMS segment," Dr. Bansi Lal added.


Challenges and Opportunities in CRAMS Business
Highlights of Presentation by Dr. Bansi Lal at the “CII Lifesciences Conclave 2007” in Delhi, India, October 12 - 13, 2007

Emerging Global Scenario
• Introduction of new drugs on global scale has come down.
  Cost per molecule introduction has further gone up > US $ 1 billion.
• Pressure on cost & profit is very high.
• Competition is increasing every day.
• Products are going out of patents. 
• Globalization is getting real.
• Old models of doing business are not effective.
• Mergers have been partially successful.
• Business needs a paradigm shift.
• Hence outsourcing is a must.
• Therefore the birth of CRAMS.


Areas of Contract Research & Manufacturing

• APIs
• Intermediates
• Drug Discovery
• Formulations
• Clinical trials
• Other Chemicals

APIs, Other Chemicals & Formulations
• Develop API (CTD) in cGMP & non GMP
• Material for Stability / toxicology study
• Kilo scale production, Material for   Preclinical, Phase I, II.
• Process development, optimization and   validation
• HAZOP, Automation, New Technology   generation
• Specialty chemicals, Agrochemicals
• Diagnostics, Electronics, Textiles
• Formulations of Old and New Molecules
• PDL --> Kilo scale --> Small scale -->   Medium scale --> Large scale

  Disclaimer:
 "The information in this e-mail and any attachmen
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 “Meet us at at CPhI India  2007, at Bombay Exhibition Centre, Mumbai, India. November  25 -  27  2007, at Hall- 5, Stand No: B12”